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Pyruvate Carboxylase-IN-1 is a potent inhibitor of pyruvate carboxylase with antiproliferative activity. It shows inhibitory effects on the growth of HepG2 and HCCLM3 cells.
Potent pyruvate carboxylase inhibitor
Exhibits antiproliferative activity
Inhibits HepG2 cell growth (IC50 1.741 μM)
Inhibits HCCLM3 cell growth (IC50 8.540 μM)
For research use only
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Ethyl pyruvate is a simple derivative of the endogenous metabolite pyruvate Ethyl pyruvate is an HMGB1 release inhibitor Ethyl pyruvate can induce apoptosis by autophagy Ethyl pyruvate has anti-inflammatory antioxidant and anti-tumor activity Ethyl pyruvate can be used in the study of neurodegenerative diseases such as Alzheimer s and Parkinson s disease[1][2][3][4][5]
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